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℡ 4000-520-616
℡ 4000-520-616
Cusabio/Rat IgG Fc fragment/10mg/CSB-NP007001r
产品编号:CSB-NP007001r
市  场 价:¥0.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>球蛋白>
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Cusabio/Rat IgG Fc fragment/10mg/CSB-NP007001r
商品介绍
  • Specification

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CodeCSB-NP007001r
Product TypeNative Protein
SizeUS$2000Purchase it in Cusabio online store(Shop online in the US.Customers outside the US, please order from local distributors.)
RelevanceThe fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody"s two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2, 6 linked sialic acid residues. The other part of an antibody, called the Fab region, contains variable sections that define the specific target that the antibody can bind. By contrast, the Fc region of all antibodies in a class are the same for each species; they are constant rather than variable. The Fc region is, therefore, sometimes incorrectly termed the "fragment constant region".
Image
  • SDS-PAGE - Rat IgG Fc fragment

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Tested ApplicationsELISA, WB, SDS-PAGE
FormLiquid
Storage BufferPBS, pH 7.4
AliasFragment crystallizable region
Biological_ActivityNot test
Purity>95% (SDS-PAGE)
SequenceFull length protein
Research AreaImmunology
SourceRat serum IgG digested with papain
Protein NamesRat IgG Fc fragment
StorageAliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
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武汉华美生物工程有限公司成立于2007年12月,注册资金为5000万元,是一家集科研、生 产、销售为一体的国家高新技术企业,以食品安全检测产品生产、诊断试剂原料供应、科 研试剂生产、生物技术服务为核心,主要为国内外知名的医药研发公司、诊断试剂生产厂 家、政府监管检测机构、高等院校、企业及科研院所等提供相关产品及定制化的技术服务 。公司拥有6个研发平台,分别为食品安全检测产品开发平台、高通量基因克隆平台、蛋白质 组学的生物标记物高通量筛选平台、生物标记物的免疫性检测方法快速建立平台、四大表 达系统的重组蛋白表达平台和科研及诊断用单多抗制备平台。以技术为核心、视质量为生 命、奉用户为上帝,竭诚为您提供性价比较高的检测产品及无微不至的售后服务。业务范围 主营基因、重组蛋白、抗体、ELISA试剂盒、食品安全检测试剂盒及诊断试剂原料产品。 

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