Recombinant Human Retroviral-like aspartic protease 1(ASPRV1)

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Code	CSB-CF684475HU
Size	US$1235
Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-CF684475HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ASPRV1. Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-CF684475HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) ASPRV1.
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Target Data

Product Details

Purity	Greater than 85% as determined by SDS-PAGE.
Target Names	ASPRV1
Uniprot No.	Q53RT3
Research Area	Cell Biology
Alternative Names	ASPRV1; SASPRetroviral-like aspartic protease 1; EC 3.4.23.-; Skin-specific retroviral-like aspartic protease; SASPase; Skin aspartic protease; TPA-inducible aspartic proteinase-like protein; TAPS
Species	Homo sapiens (Human)
Source	in vitro E.coli expression system
Expression Region	191-326aa
Target Protein Sequence	SMGKGYYLKGKIGKVPVRFLVDSGAQVSVVHPNLWEEVTDGDLDTLQPFENVVKVANGAEMKILGVWDTAVSLGKLKLKAQFLVANASAEEAIIGTDVLQDHNAILDFEHRTCTLKGKKFRLLPVGGSLEDEFDLENote: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight	19.9 kDa
Protein Length	Full Length of Mature Protein
Tag Info	N-terminal 10xHis-tagged and C-terminal Myc-tagged
Form	Liquid or Lyophilized powder Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.Note: If you have any special requirement for the glycerol content, please remark when you place the order.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs	Protein FAQs
Storage Condition	Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time	Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA	Please contact us to get it.

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Target Data

Gene References into Functions	results failed to find an association between ASPRV1 gene mutations and atopic eczema or clinically dry skin in the European populations studied PMID: 22318384 SASPase activity is indispensable for processing profilaggrin and maintaining the texture and hydration of the stratum corneum. PMID: 21542132 Identification and characterization of a new member of the aspartic proteases family, a unique epidermal retroviral-like protease, Skin ASpartic Protease. PMID: 16098038 Taps expression is negatively associated with dedifferentiation and malignant progression in squamous cell carcinomas of the skin. PMID: 16565508
Subcellular Location	Membrane, Single-pass membrane protein
Tissue Specificity	Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent f
Database Links	HGNC: 26321 OMIM: 611765 KEGG: hsa:151516 STRING: 9606.ENSP00000315383 UniGene: Hs.516253

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武汉华美生物工程有限公司成立于2007年12月，注册资金为5000万元，是一家集科研、生产、销售为一体的国家高新技术企业，以食品安全检测产品生产、诊断试剂原料供应、科研试剂生产、生物技术服务为核心，主要为国内外知名的医药研发公司、诊断试剂生产厂家、政府监管检测机构、高等院校、企业及科研院所等提供相关产品及定制化的技术服务。公司拥有6个研发平台，分别为食品安全检测产品开发平台、高通量基因克隆平台、蛋白质组学的生物标记物高通量筛选平台、生物标记物的免疫性检测方法快速建立平台、四大表达系统的重组蛋白表达平台和科研及诊断用单多抗制备平台。以技术为核心、视质量为生命、奉用户为上帝，竭诚为您提供性价比较高的检测产品及无微不至的售后服务。业务范围主营基因、重组蛋白、抗体、ELISA试剂盒、食品安全检测试剂盒及诊断试剂原料产品。

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